CBG is the abbreviation of Cannabigerol, one of the many compounds contained in Marijuana. It’s a beneficial substance, and many don’t realize its value. THC is Tetrahydrocannabinol, and Cannabidiol is CBD. People are familiar with these cannabis-derived natural products. There’s been research and media attention given to both. So don’t confuse CBG with either THC or CBD.

Basically, people use cannabis recreationally owing to the impact THC has on them–that’s where the “high” comes from. This is what gives marijuana its reputation as an intoxicant. Meanwhile, CBD is a health product used to assuage inflammation and pain. There’s no intoxication from CBD, the benefit is all medicinal. In Cannabis, CBD and THC can commonly be found in high quantities, with “Hemp” having higher quotients of CBD.

CBG isn’t found in high quantities among traditional cannabis plants, so it’s often lost in the shuffle when it comes to other, more popular cannabinoids. With that in mind, we’re going to dive in and take a closer look throughout this writing.

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Exploring CBG’s History

The Israelis discovered CBG in 1964. Mechoulam and Gaoni were well-known scientists who found ways of separating out THC, CBD, and CBG from cannabis. This led to big changes in the marijuana community.

Like CBD, CBG does not produce any sort of “high”. Also, owing to varying means of extraction and it being a less robust aspect of cannabis, it’s usually extracted from industrial grow operations or associated products. As you may have guessed, even though some benefits of CBG are known, research into this compound is relatively new. There are key properties to CBG which bear examination, but as yet not all that can be known has been discovered regarding this compound.

CBG Pharmacology

Like other cannabis-derived substances, it is the endocannabinoid system that reacts with CBG. If you’re unfamiliar, varying compounds of the endocannabinoid variety function within human biology naturally. These play a part in regulating varying physiological aspects of healthy homeostasis. Two primary receptors can be found in the body to this purpose:

  • CB-1
  • CB-2

CB-1 receptors are in the brain and nervous system. CB-2 receptors are primarily contained in the body’s immune system. CBG interacts with CB-2 receptors. It’s been discovered in some situations, other components may be blocked from binding to CB-1 receptors by CBG. Total interaction of CBG as relates to the body is contemporarily understood as “The Entourage Effect“.


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Power of CBG Hemp Flower

Medical Research As Related To CBG

There is research to suggest medical support that’s both psychological and physiological develops from proper CBG ingestion. It has also been seen that some sort of anti-inflammatory effect defines this compound, making it ideal in helping bodies heal. A researcher named Borelli conducted investigations into this anti-inflammatory impact around 2013. Mice with a bowel disease were given CBG. The perceived positive effect of CBG on these bowel inflammation issues prompted increased research into possible human applications.

Should confirmed positive results develop, conditions like colitis will likely be treated using CBG supplementation. Also, conditions that are chronic such as arthritis could see some relief via CBG. Additional medical conditions that it may treat include:

  • Diabetes
  • Unhealthy Blood Pressure
  • Certain Cancers

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The “Neuroprotective Effects” Associated With CBG

Nervous system damage can be therapeutically impacted owing to the associated oxidative effect CBG has on the body. A researcher named Sara Valdeolivas looked into this in 2015, finding a clear effect between mice suffering from Huntington’s disease, and CBG supplementation.

What they discovered were that neurons were protected from increased damage via CBG, even as the disease was simultaneously halted from further progression.

Anti-Microbial Properties Of CBG

At McMaster University, an early 2020 study was conducted to determine if CBG had an impact on Staphylococcus aureus (MRSA) in mice. Many antibiotics are resisted by MRSA, and so it has a notorious reputation.

It was determined through this research that indeed CBG could help organisms resist bacteria otherwise unaffected by drugs. Biofilms were reduced as CBG hampered the spread of bacteria. The way in which this was done was a CBG “attack” on resistant bacteria membranes.

The breakthrough has been noted by researchers. It is hoped that the toxicity of CBG can be properly harnessed such that it only works on bacterial cells, and doesn’t impact healthy cells in their vicinity.


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Properties of CBG


Appetite Enhancing Properties Of CBG

In terms of appetite stimulation, many scientists have noted CBG incorporates this benefit. A scientist named Brierley discovered this through research conducted by him and his team in 2016.

Some rats got placebos, the others got CBG. CBG-supplemented rats ate twice as much as their control group counterparts without showing any negative effects. For conditions such as anorexia or cachexia, CBG is a promising compound.

CBG Can Have Therapeutic Impact On Bladder Issues

Urinary incontinence is embarrassing, chronic, and painful–CBG can treat it; at least according to a 2015 study conducted by a scientist named Pagano and his team. Again, mice were treated for bladder issues using CBG, and results indicted acetylcholine-related bladder dysfunction could be reduced using this cannabis-derived compound.

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The Takeaway

There are many promising effects suggested by CBG research, but the investigation of this compound is not yet finished. While it can’t be concretely stated that CBG is superior to CBD (or vice versa), research keeps turning up positive benefits. At the end of the day, it’s astonishing the level of health conditions cannabinoids are able to treat or cure.

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